Pub. Date : 2015 Jan
PMID : 25380156
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | c-Src, ERK1/2 and Rho kinase mediate hydrogen peroxide-induced vascular contraction in hypertension: role of TXA2, NAD(P)H oxidase and mitochondria. | Hydrogen Peroxide | mitogen activated protein kinase 3 | Rattus norvegicus |
| 2 | The ERK1/2 inhibitor PD98059 reduced H2O2 but not U46619-induced contraction only in SHR arteries. | Hydrogen Peroxide | mitogen activated protein kinase 3 | Rattus norvegicus |
| 3 | The effects induced by H2O2 were abolished by inhibitors of TXA2 synthase, ERK1/2 and c-Src. | Hydrogen Peroxide | mitogen activated protein kinase 3 | Rattus norvegicus |
| 4 | Moreover, ERK1/2 activation contributes to H2O2 contraction in SHR through effects on mitochondria/NAD(P)H Oxidase. | Hydrogen Peroxide | mitogen activated protein kinase 3 | Rattus norvegicus |