Title : Klotho up-regulates renal calcium channel transient receptor potential vanilloid 5 (TRPV5) by intra- and extracellular N-glycosylation-dependent mechanisms.

Pub. Date : 2014 Dec 26

PMID : 25378396






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Secreted Klotho (sKL) up-regulates the TRPV5 calcium channel from the cell exterior by removing sialic acids from N-glycan of the channel and inhibiting its endocytosis. Sialic Acids klotho Homo sapiens