Title : Characterizing the PK/PD relationship for inhibition of capsaicin-induced dermal vasodilatation by MK-3207, an oral calcitonin gene related peptide receptor antagonist.

Pub. Date : 2015 May

PMID : 25377933






2 Functional Relationships(s)
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1 Characterizing the PK/PD relationship for inhibition of capsaicin-induced dermal vasodilatation by MK-3207, an oral calcitonin gene related peptide receptor antagonist. Capsaicin calcitonin related polypeptide alpha Homo sapiens
2 In the model, CGRP release is provoked after dermal capsaicin application, by activating transient receptor potential vanilloid-type-1 (TRPV1) receptors at peripheral sensory nerves. Capsaicin calcitonin related polypeptide alpha Homo sapiens