Title : A functional approach reveals a genetic and physical interaction between ribonucleotide reductase and CHK1 in mammalian cells.

Pub. Date : 2014

PMID : 25375241






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Ribonucleotide reductase (RNR) enzyme is composed of the homodimeric RRM1 and RRM2 subunits, which together form a heterotetramic active enzyme that catalyzes the de novo reduction of ribonucleotides to generate deoxyribonucleotides (dNTPs), which are required for DNA replication and DNA repair processes. Deoxyribonucleotides ribonucleotide reductase regulatory subunit M2 Homo sapiens