Title : Calcitonin gene-related peptide increases cAMP, tension, and rate in rat atria.

Pub. Date : 1989 Feb

PMID : 2537038






1 Functional Relationships(s)
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1 Compared with norepinephrine (NE), CGRP was 14-fold more potent at increasing rate [50% effective concentration (EC50) = 4.55 +/- 0.48 nM for CGRP and 64.8 +/- 10.5 nM for NE] and 60-fold more potent at increasing contractile force (EC50 = 3.31 +/- 0.57 nM for CGRP and 201 +/- 18 nM for NE). Norepinephrine calcitonin-related polypeptide alpha Rattus norvegicus