Title : Exogenous addition of arachidonic acid to the culture media enhances the functionality of dendritic cells for their possible use in cancer immunotherapy.

Pub. Date : 2014

PMID : 25369453






1 Functional Relationships(s)
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1 Thus addition of AA to the culture media is skewing the DCs towards the secretion of more IL-12 and less of IL-10 along with the restoration of eicosanoids levels in a COX-2 mediated pathway thereby enhancing the functionality of these cells to be used as a potent cellular vaccine. Eicosanoids mitochondrially encoded cytochrome c oxidase II Homo sapiens