Title : Single-cell screening of cytosolic [Ca(2+)] reveals cell-selective action by the Alzheimer's Aβ peptide ion channel.

Pub. Date : 2015 Mar

PMID : 25366568






1 Functional Relationships(s)
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1 Moreover, the results obtained of using potent inhibitors of Abeta cation channels such as Zn(2+) and the small peptide NA7 add further proof to the suggestion that the long-term increases in cytosolic [Ca(2+)] in cells stressed by continuous exposure to Abeta is the result of Abeta ion channel activity. Zinc amyloid beta precursor protein Homo sapiens