Pub. Date : 2014 Dec
PMID : 25362535
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inducing effect of clofibric acid on stearoyl-CoA desaturase in intestinal mucosa of rats. | Clofibric Acid | stearoyl-CoA desaturase | Rattus norvegicus |
| 2 | Upon the treatment with clofibric acid, SCD was induced and the gene expression of SCD1, SCD2, and fatty acid elongase (Elovl) 6 was up-regulated, but that of Elovl5 was unaffected. | Clofibric Acid | stearoyl-CoA desaturase | Rattus norvegicus |
| 3 | Upon the treatment with clofibric acid, SCD was induced and the gene expression of SCD1, SCD2, and fatty acid elongase (Elovl) 6 was up-regulated, but that of Elovl5 was unaffected. | Clofibric Acid | stearoyl-CoA desaturase | Rattus norvegicus |
| 4 | These results indicate that intestinal mucosa significantly changes its MUFA profile in response to challenges by clofibric acid and a fat-free diet and suggest that up-regulation of the gene expression of SCD along with Elovl6 is indispensable to elevate the proportion of 18:1n-9 in intestinal mucosa. | Clofibric Acid | stearoyl-CoA desaturase | Rattus norvegicus |