Title : Biochemical, mechanistic, and spectroscopic characterization of metallo-β-lactamase VIM-2.

Pub. Date : 2014 Nov 25

PMID : 25356958






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 This study examines metal binding to metallo-beta-lactamase VIM-2, demonstrating the first successful preparation of a Co(II)-substituted VIM-2 analogue. Metals mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 Spectroscopic studies of the half- and fully metal loaded enzymes show that both Zn(II) and Co(II) bind cooperatively, where the major species present, regardless of stoichiometry, are apo- and di-Zn (or di-Co) enzymes. Metals mitochondrially encoded cytochrome c oxidase II Homo sapiens