Title : MiR-133b contributes to arsenic-induced apoptosis in U251 glioma cells by targeting the hERG channel.

Pub. Date : 2015 Apr

PMID : 25355491






3 Functional Relationships(s)
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Protein Name
Organism
1 The present study was designed to determine whether the expression of hERG gene is regulated by miR-133b or miR-34a, thereby contributing to the anti-proliferation effect of arsenic trioxide (ATO) in U251 human glioma cells. Arsenic Trioxide ETS transcription factor ERG Homo sapiens
2 The present study was designed to determine whether the expression of hERG gene is regulated by miR-133b or miR-34a, thereby contributing to the anti-proliferation effect of arsenic trioxide (ATO) in U251 human glioma cells. Arsenic Trioxide ETS transcription factor ERG Homo sapiens
3 The transfection of anti-miR-133b oligonucleotide (AMO-133b) remarkably prevented the decrease of hERG protein by 5 muM ATO treatment for 24 h in U251 cells, whereas anti-miR-34a oligonucleotide (AMO-34a) did not exhibit recuperated effect. Arsenic Trioxide ETS transcription factor ERG Homo sapiens