Title : Interleukin-2 and subunit alpha of its soluble receptor in autoimmune Addison's disease--an association study and expression analysis.

Pub. Date : 2015 Mar

PMID : 25347332






3 Functional Relationships(s)
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1 Only AAD cells responded to 21OH with an elevated IL2 and IL2RA mRNA synthesis (p = 0.004 and p = 0.009 versus controls, respectively), paralleled by increased supernatant levels of both cytokines (p = 0.031 and p = 0.001 versus controls). 21oh interleukin 2 receptor subunit alpha Homo sapiens
2 Carriers of the rs2104286 AA genotype demonstrated higher IL2RA mRNA (p = 0.022) and soluble IL2Ra secretion (p = 0.029) upon 21OH stimulation. 21oh interleukin 2 receptor subunit alpha Homo sapiens
3 Carriers of the rs2104286 AA genotype demonstrated higher IL2RA mRNA (p = 0.022) and soluble IL2Ra secretion (p = 0.029) upon 21OH stimulation. 21oh interleukin 2 receptor subunit alpha Homo sapiens