Title : Disturbances of Tryptophan Metabolism and Risk of Depression in HCV Patients Treated with IFN-Alpha.

Pub. Date : 2014 Feb 25

PMID : 25346938






2 Functional Relationships(s)
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1 Disturbances of tryptophan (TRP) metabolism might contribute to development of IFN-alpha-associated depression due to IFN-alpha-induced activation of indoleamine 2,3-dioxygenase (IDO), a rate-limiting enzyme of TRP-kynurenine (KYN) metabolism. 4,6-dichlorokynurenine interferon alpha 1 Homo sapiens
2 Disturbances of tryptophan (TRP) metabolism might contribute to development of IFN-alpha-associated depression due to IFN-alpha-induced activation of indoleamine 2,3-dioxygenase (IDO), a rate-limiting enzyme of TRP-kynurenine (KYN) metabolism. 4,6-dichlorokynurenine interferon alpha 1 Homo sapiens