Title : Synthetic cannabimimetic agents metabolized by carboxylesterases.

Pub. Date : 2015 Jul

PMID : 25346527






2 Functional Relationships(s)
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1 Carboxylesterase 1 (CES1) was identified as the major human hepatic and pulmonary enzyme responsible for the amide hydrolysis.We employed similar studies to identify the esterase(s) involved in the previously described hydrolytic metabolism of two quinolineindole synthetic cannabinoids, PB-22 and 5F-PB-22, as well as the closely related compound, BB-22. quinolineindole carboxylesterase 1 Homo sapiens
2 Carboxylesterase 1 (CES1) was identified as the major human hepatic and pulmonary enzyme responsible for the amide hydrolysis.We employed similar studies to identify the esterase(s) involved in the previously described hydrolytic metabolism of two quinolineindole synthetic cannabinoids, PB-22 and 5F-PB-22, as well as the closely related compound, BB-22. quinolineindole carboxylesterase 1 Homo sapiens