Title : [Isolation of fibronectin peptide fragments of various sizes and biological activity using affinity chromatography on an immobilized plasmin].

Pub. Date : 1989 Nov-Dec

PMID : 2534245






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Plasmin, immobilized on Sepharose, was used for isolation of human blood plasma fibronectin fragments obtained after proteolysis. Sepharose fibronectin 1 Homo sapiens
2 Under definite conditions the major part of the fibronectin fragments, liberated during proteolysis, remained to be bound to plasmin-Sepharose. Sepharose fibronectin 1 Homo sapiens
3 These unbound to plasmin-Sepharose fibronectin fragments were found to stimulate proliferation of human embryonal fibroblasts in cell culture, whereas the plasmin-Sepharose bound peptides did not exhibit any effects on proliferation. Sepharose fibronectin 1 Homo sapiens