Title : Simvastatin induces NFκB/p65 down-regulation and JNK1/c-Jun/ATF-2 activation, leading to matrix metalloproteinase-9 (MMP-9) but not MMP-2 down-regulation in human leukemia cells.

Pub. Date : 2014 Dec 15

PMID : 25316568






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Treatment with SP600125 (a JNK inhibitor) or knock-down of JNK1 reduced MMP-2 expression in simvastatin-treated cells. pyrazolanthrone matrix metallopeptidase 2 Homo sapiens