Pub. Date : 2015 Apr
PMID : 25311385
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Morphine is subject to efflux via P-glycoprotein transporter encoded by ABCB1, also known as MDR1. | Morphine | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Morphine is subject to efflux via P-glycoprotein transporter encoded by ABCB1, also known as MDR1. | Morphine | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | ABCB1 polymorphisms may affect blood-brain barrier transport of morphine and therefore individual response to its central analgesic and adverse effects. | Morphine | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | This study aimed to determine specific associations between common ABCB1 genetic variants and clinically important outcomes including RD and RD resulting in prolonged stay in hospital with intravenous morphine in a homogenous pediatric surgical pain population of 263 children undergoing tonsillectomy. | Morphine | ATP binding cassette subfamily B member 1 | Homo sapiens |