Pub. Date : 2015 Jan
PMID : 25310623
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 5-FU resistance abrogates the amplified cytotoxic effects induced by inhibiting checkpoint kinase 1 in p53-mutated colon cancer cells. | Fluorouracil | tumor protein p53 | Homo sapiens |
| 2 | In contrast, in p53-deficient, 5-FU-resistant (5FUR) colon cancer cells that we developed, 5-FU enhanced DNA damage but did not induce Chk1/ATM activation or cell cycle arrest. | Fluorouracil | tumor protein p53 | Homo sapiens |
| 3 | In contrast, in p53-deficient, 5-FU-resistant (5FUR) colon cancer cells that we developed, 5-FU enhanced DNA damage but did not induce Chk1/ATM activation or cell cycle arrest. | Fluorouracil | tumor protein p53 | Homo sapiens |