Title : +TIP EB1 downregulates paclitaxel‑induced proliferation inhibition and apoptosis in breast cancer cells through inhibition of paclitaxel binding on microtubules.

Pub. Date : 2015 Jan

PMID : 25310526






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 p53 and Bax were upregulated and Bcl2 was downregulated in the EB1-depleted PTX-treated MCF-7 cells, indicating that the apoptosis occurs via a p53-dependent pathway. Paclitaxel tumor protein p53 Homo sapiens
2 p53 and Bax were upregulated and Bcl2 was downregulated in the EB1-depleted PTX-treated MCF-7 cells, indicating that the apoptosis occurs via a p53-dependent pathway. Paclitaxel tumor protein p53 Homo sapiens