Title : P2X7 receptor blockade protects against cisplatin-induced nephrotoxicity in mice by decreasing the activities of inflammasome components, oxidative stress and caspase-3.

Pub. Date : 2014 Nov 15

PMID : 25308879






2 Functional Relationships(s)
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1 P2X7 receptor blockade protects against cisplatin-induced nephrotoxicity in mice by decreasing the activities of inflammasome components, oxidative stress and caspase-3. Cisplatin caspase 3 Mus musculus
2 These effects were associated with the significantly reduced levels of NLRP3 inflammasome components, oxidative stress, p53 and caspase-3 in renal tissues in cisplatin-induced nephrotoxicity. Cisplatin caspase 3 Mus musculus