Title : Metformin displays anti-myeloma activity and synergistic effect with dexamethasone in in vitro and in vivo xenograft models.

Pub. Date : 2015 Jan 28

PMID : 25305450






1 Functional Relationships(s)
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1 Western blot showed that metformin activated caspase 3, caspase 9, PARP-1, Bak, and p21 and inactivated Mcl-1, HIAP-1, cyclin D1, CDK4, and CDK6. Metformin cyclin D1 Homo sapiens