Title : Permanent culture of macrophages at physiological oxygen attenuates the antioxidant and immunomodulatory properties of dimethyl fumarate.

Pub. Date : 2015 May

PMID : 25303683






1 Functional Relationships(s)
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1 At 20% O2, DMF induced a stronger antioxidant response compared to 5% O2 as evidenced by a higher expression of heme oxygenase-1, NAD(P)H:quinone oxydoreductase-1 and superoxide dismutase-2. Dimethyl Fumarate heme oxygenase 1 Homo sapiens