Title : Comparison of the immunosuppressive properties of milk growth factor and transforming growth factors beta 1 and beta 2.

Pub. Date : 1989 Nov 15

PMID : 2530275






3 Functional Relationships(s)
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1 MGF, pTGF-beta 1, and pTGF-beta 2 decreased mitogen-induced [3H]thymidine incorporation by 30 to 75% in a dose-dependent manner. Tritium insulin like growth factor 1 Homo sapiens
2 Furthermore, MGF, pTGF-beta 1, and pTGF-beta 2 also decreased IL-2 mediated [3H]thymidine incorporation into human PBL Con A blasts and the IL-4-mediated [3H]thymidine incorporation of purified T lymphocytes costimulated with PDBu by 70%. Tritium insulin like growth factor 1 Homo sapiens
3 Furthermore, MGF, pTGF-beta 1, and pTGF-beta 2 also decreased IL-2 mediated [3H]thymidine incorporation into human PBL Con A blasts and the IL-4-mediated [3H]thymidine incorporation of purified T lymphocytes costimulated with PDBu by 70%. Tritium insulin like growth factor 1 Homo sapiens