Title : Oxidative stress preferentially induces a subtype of micronuclei and mediates the genomic instability caused by p53 dysfunction.

Pub. Date : 2014 Dec

PMID : 25302047






1 Functional Relationships(s)
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1 Evidence showed that tumor suppressor p53 plays an important role in regulating the generation of cellular ROS, either by reducing oxidative stress under physiological and mildly stressed conditions, or by promoting oxidative stress under highly stressed conditions. Reactive Oxygen Species tumor protein p53 Homo sapiens