Pub. Date : 2014
PMID : 25299210
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Manganese superoxide dismutase (Mn-SOD) showed a similar dose-dependent reduction in cells undergoing apoptosis, while levels of the intracellular calcium ion exchange maker calbindin-D9k were decreased in apoptosis (1.0 to 5 microM CsA), but unchanged in autophagy. | Cyclosporine | superoxide dismutase 2 | Rattus norvegicus |
| 2 | Manganese superoxide dismutase (Mn-SOD) showed a similar dose-dependent reduction in cells undergoing apoptosis, while levels of the intracellular calcium ion exchange maker calbindin-D9k were decreased in apoptosis (1.0 to 5 microM CsA), but unchanged in autophagy. | Cyclosporine | superoxide dismutase 2 | Rattus norvegicus |
| 3 | In conclusion, these results suggest that CsA induction of apoptotic or autophagic cell death in rat pituitary GH3 cells depends on the relative expression of factors and correlates with Bcl-2 and Mn-SOD levels. | Cyclosporine | superoxide dismutase 2 | Rattus norvegicus |