Title : CerS2 haploinsufficiency inhibits β-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance.

Pub. Date : 2014 Oct 7

PMID : 25295789






1 Functional Relationships(s)
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1 Collectively, these studies reveal that altering sphingolipid acylation patterns impacts hepatic steatosis and insulin sensitivity and identify CerS6 as a possible therapeutic target for treating metabolic diseases associated with obesity. Sphingolipids insulin Homo sapiens