Pub. Date : 2014 Nov
PMID : 25295542
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | IL-1beta cleavage and secretion were impaired in HO-1-deficient macrophages, and CO-dependent processing of IL-1beta required the presence of bacteria-derived ATP. | Adenosine Triphosphate | interleukin 1 beta | Mus musculus |
2 | The ATP then bound to macrophage nucleotide P2 receptors, resulting in activation of the NALP3/IL-1beta inflammasome to amplify bacterial phagocytosis by macrophages. | Adenosine Triphosphate | interleukin 1 beta | Mus musculus |