Title : PP2A: The Achilles Heal in MDS with 5q Deletion.

Pub. Date : 2014

PMID : 25295231






1 Functional Relationships(s)
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1 Through its inhibitory effect on PP2A, lenalidomide stabilizes MDM2 to restore p53 degradation in erythroid precursors, with subsequent arrest in G2/M. Lenalidomide MDM2 proto-oncogene Homo sapiens