Title : Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex.

Pub. Date : 2014 Oct 20

PMID : 25288394






1 Functional Relationships(s)
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1 Genetic studies have shown that the tuberous sclerosis complex (TSC) 1-TSC2-mammalian target of Rapamycin (mTOR) and the Hippo-Yes-associated protein 1 (YAP) pathways are master regulators of organ size, which are often involved in tumorigenesis. Sirolimus TSC complex subunit 1 Mus musculus