Title : Elotuzumab enhances natural killer cell activation and myeloma cell killing through interleukin-2 and TNF-α pathways.

Pub. Date : 2015 Jan

PMID : 25287778






1 Functional Relationships(s)
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1 In co-culture assays, TNF-alpha directly increased NK cell activation and myeloma cell death with elotuzumab or elotuzumab plus lenalidomide, and neutralizing TNF-alpha decreased NK cell activation and myeloma cell death with elotuzumab. Lenalidomide tumor necrosis factor Homo sapiens