Title : Biphasic modulation of paracellular claudin-5 expression in mouse brain endothelial cells is mediated through the phosphoinositide-3-kinase/AKT pathway.

Pub. Date : 2014 Dec

PMID : 25281324






2 Functional Relationships(s)
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1 We hypothesize that 3-chloropropanediol-induced modulation of tight junction protein expression is mediated through the phosphoinositide-3-kinase (PI3K)/AKT pathway. alpha-Chlorohydrin thymoma viral proto-oncogene 1 Mus musculus
2 Western blot and immunofluorescence studies showed increased p85-PI3K expression and transitory increased AKT (Thr308) phosphorylation at 15 and 30 minutes after 3-chloropropanediol administration. alpha-Chlorohydrin thymoma viral proto-oncogene 1 Mus musculus