Title : Pioglitazone reduces lipid droplets in cholesterolosis of the gallbladder by increasing ABCA1 and NCEH1 expression.

Pub. Date : 2015 Jan

PMID : 25280398






1 Functional Relationships(s)
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1 In conclusion, we observed that pioglitazone increased ABCA1 expression in an LXR-dependent manner and NCEH1 expression in an LXRalpha-independent manner, which mobilized CE hydrolysis and cholesterol efflux to reduce lipid droplet content in cholesterolosis GBECs. Pioglitazone nuclear receptor subfamily 1 group H member 3 Homo sapiens