Pub. Date : 2014 Jul-Sep
PMID : 25280024
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Mast cells mature under local tissue microenvironmental factors and are necessary for the development of allergic reactions, through crosslinking of their surface receptors for IgE (FcepsilonRI), leading to degranulation and the release of vasoactive, pro-inflammatory and nociceptive mediators that include histamine, pro-inflammatory and anti-inflammatory cytokines and proteolytic enzymes. | Histamine | Fc epsilon receptor Ia | Homo sapiens |