Title : An adenosine A1 agonist 2-chloro-N6 cyclopentyladenosine inhibits the angiotensin II-induced cardiomyocyte hypertrophy through the calcineurin pathway.

Pub. Date : 2014

PMID : 25277512






6 Functional Relationships(s)
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1 An adenosine A1 agonist 2-chloro-N6 cyclopentyladenosine inhibits the angiotensin II-induced cardiomyocyte hypertrophy through the calcineurin pathway. 2-chloro-N(6)cyclopentyladenosine angiotensinogen Rattus norvegicus
2 OBJECTIVES: The aim of this investigation was to study the underlying mechanism of an adenosine A1 receptor agonist 2-chloro-N6 cyclopentyladenosine (CCPA) inhibiting cardiomyocyte hypertrophy induced by angiotensin II (AngII). 2-chloro-N(6)cyclopentyladenosine angiotensinogen Rattus norvegicus
3 OBJECTIVES: The aim of this investigation was to study the underlying mechanism of an adenosine A1 receptor agonist 2-chloro-N6 cyclopentyladenosine (CCPA) inhibiting cardiomyocyte hypertrophy induced by angiotensin II (AngII). 2-chloro-N(6)cyclopentyladenosine angiotensinogen Rattus norvegicus
4 OBJECTIVES: The aim of this investigation was to study the underlying mechanism of an adenosine A1 receptor agonist 2-chloro-N6 cyclopentyladenosine (CCPA) inhibiting cardiomyocyte hypertrophy induced by angiotensin II (AngII). 2-chloro-N(6)cyclopentyladenosine angiotensinogen Rattus norvegicus
5 OBJECTIVES: The aim of this investigation was to study the underlying mechanism of an adenosine A1 receptor agonist 2-chloro-N6 cyclopentyladenosine (CCPA) inhibiting cardiomyocyte hypertrophy induced by angiotensin II (AngII). 2-chloro-N(6)cyclopentyladenosine angiotensinogen Rattus norvegicus
6 CONCLUSION: The A1 receptor agonist CCPA could significantly inhibit AngII-induced cardiomyocyte hypertrophy via the calcineurin signaling pathway. 2-chloro-N(6)cyclopentyladenosine angiotensinogen Rattus norvegicus