Pub. Date : 2014 Dec
PMID : 25277138
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rifaximin treatment significantly decreased the number of colon tumors induced by AOM/DSS treatment in PXR-humanized mice, but not wild-type or Pxr-null mice. | Rifaximin | nuclear receptor subfamily 1, group I, member 2 | Mus musculus |
| 2 | Additionally, rifaximin treatment markedly increased the survival rate of PXR-humanized mice, but not wild-type or Pxr-null mice. | Rifaximin | nuclear receptor subfamily 1, group I, member 2 | Mus musculus |
| 3 | Nuclear factor kappa-light-chain-enhancer of activated B cells-mediated inflammatory signaling was upregulated in AOM/DSS-treated mice, and inhibited by rifaximin in PXR-humanized mice. | Rifaximin | nuclear receptor subfamily 1, group I, member 2 | Mus musculus |