Title : Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition.

Pub. Date : 2014 Nov 24

PMID : 25264584






3 Functional Relationships(s)
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1 Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition. Oleanolic Acid protein tyrosine phosphatase non-receptor type 1 Homo sapiens
2 Pentacyclic acid triterpenes such as oleanolic acid (OA) have proved to be excellent PTP-1B inhibitors, thus, the purpose of current work was to generate a series of derivatives that improve the pharmacological effect of OA. Oleanolic Acid protein tyrosine phosphatase non-receptor type 1 Homo sapiens
3 Pentacyclic acid triterpenes such as oleanolic acid (OA) have proved to be excellent PTP-1B inhibitors, thus, the purpose of current work was to generate a series of derivatives that improve the pharmacological effect of OA. Oleanolic Acid protein tyrosine phosphatase non-receptor type 1 Homo sapiens