Title : Binding of polyunsaturated fatty acids to LXRα and modulation of SREBP-1 interaction with a specific SCD1 promoter element.

Pub. Date : 2014 Dec

PMID : 25264165






1 Functional Relationships(s)
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1 Polyunsaturated docosahexaenoic acid (DHA, C22:6), eicosapentaenoic acid (EPA, C20:5) and arachidonic acid (AA, C20:4) were able to reduce SREBP-1 binding to SCD1 promoter, while saturated stearic acid (SA, C18:0) did not give any effect. Arachidonic Acid stearoyl-CoA desaturase Homo sapiens