Title : Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping.

Pub. Date : 2014 Nov 1

PMID : 25262942






1 Functional Relationships(s)
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1 In this study, we further explored SAR through a combination of traditional medicinal chemistry and structure-based drug design, resulting in a novel scaffold (benzamide) with selectivity against protein kinases. benzamide sarcosine dehydrogenase Homo sapiens