Title : Dipeptide prodrug approach to evade efflux pumps and CYP3A4 metabolism of lopinavir.

Pub. Date : 2014 Dec 10

PMID : 25261710






1 Functional Relationships(s)
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1 In the present study, dipeptide prodrug approach was employed to circumvent efflux pumps (P-gp and MRP2) and CYP3A4 mediated metabolism of LPV. Dipeptides ATP binding cassette subfamily C member 2 Canis lupus familiaris