Title : Efficacy of different beta-blockers in the treatment of long QT syndrome.

Pub. Date : 2014 Sep 30

PMID : 25257637






2 Functional Relationships(s)
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1 In LQT1, the risk reduction for first cardiac events was similar among the 4 beta-blockers, but in LQT2, nadolol provided the only significant risk reduction (hazard ratio: 0.40 [0.16 to 0.98]). Nadolol potassium voltage-gated channel subfamily H member 2 Homo sapiens
2 CONCLUSIONS: Although the 4 beta-blockers are equally effective in reducing the risk of a first cardiac event in LQTS, their efficacy differed by genotype; nadolol was the only beta-blocker associated with a significant risk reduction in patients with LQT2. Nadolol potassium voltage-gated channel subfamily H member 2 Homo sapiens