Title : Impact of genetic variability in CYP2D6, CYP3A5, and ABCB1 on serum concentrations of quetiapine and N-desalkylquetiapine in psychiatric patients.

Pub. Date : 2015 Apr

PMID : 25254417






2 Functional Relationships(s)
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1 Impact of genetic variability in CYP2D6, CYP3A5, and ABCB1 on serum concentrations of quetiapine and N-desalkylquetiapine in psychiatric patients. Quetiapine Fumarate cytochrome P450 family 3 subfamily A member 5 Homo sapiens
2 BACKGROUND: To investigate the impact of genetic variability in CYP2D6, CYP3A5, and ABCB1 on steady-state serum concentrations of quetiapine and the active metabolite, N-desalkylquetiapine, in psychiatric patients. Quetiapine Fumarate cytochrome P450 family 3 subfamily A member 5 Homo sapiens