Title : Development of αGlcN(1↔1)αMan-based lipid A mimetics as a novel class of potent Toll-like receptor 4 agonists.

Pub. Date : 2014 Oct 9

PMID : 25252784






1 Functional Relationships(s)
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1 alphaGlcN(1 1)alphaMan-based Lipid A mimetics (alpha,alpha-GM-LAM) induced potent activation of NF-kappaB signaling in hTLR4/hMD-2/CD14-transfected HEK293 cells and robust LPS-like cytokines expression in macrophages and dendritic cells. Lipid A CD14 molecule Homo sapiens