Title : Correlation between CYP1A1 transcript, protein level, enzyme activity and DNA adduct formation in normal human mammary epithelial cell strains exposed to benzo[a]pyrene.

Pub. Date : 2014 Nov

PMID : 25245543






2 Functional Relationships(s)
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Protein Name
Organism
1 In cells exposed to 4.0 microM BP for 12h, RNA cpn values were 251-13234 for CYP1A1, 4133-57078 for CYP1B1 and 4456-55887 for NQO1. Benzo(a)pyrene cytochrome P450 family 1 subfamily B member 1 Homo sapiens
2 In the NHMECs, BP-induced CYP1A1 RNA cpn was highly associated with BPdG (P = 0.002), but CYP1B1 and NQO1 were not. Benzo(a)pyrene cytochrome P450 family 1 subfamily B member 1 Homo sapiens