Pub. Date : 2015 Feb
PMID : 25239809
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We report that extrasynaptic NMDAR blocker memantine, reduced in a dose-dependent manner cortically induced NMDA excitatory currents in striatal neurons (recorded in zero-Mg(++) plus DNQX 10 muM). | Memantine | latexin | Homo sapiens |
| 2 | Moreover, memantine (2-4 muM) significantly reduced the NMDAR-dependent membrane potential oscillations called up and down states. | Memantine | latexin | Homo sapiens |
| 3 | After severing connections between compartments, active striatal neurons in the presence of memantine (1 muM) and CNQX (10 muM) were predominantly fast spiking interneurons (FSI). | Memantine | latexin | Homo sapiens |