Title : Mangiferin attenuates diabetic nephropathy by inhibiting oxidative stress mediated signaling cascade, TNFα related and mitochondrial dependent apoptotic pathways in streptozotocin-induced diabetic rats.

Pub. Date : 2014

PMID : 25233093






1 Functional Relationships(s)
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1 Besides, TNFalpha was released in this hyperglycemic condition, which in turn activated caspase 8, cleaved Bid to tBid and finally the mitochorndia-dependent apoptotic pathway. tBID tumor necrosis factor Rattus norvegicus