Title : Nicotinamide prolongs survival of primary cultured hepatocytes without involving loss of hepatocyte-specific functions.

Pub. Date : 1989 Mar 25

PMID : 2522446






2 Functional Relationships(s)
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1 In the nicotinamide-treated hepatocytes, albumin and tryptophan 2,3-dioxygenase mRNAs were present at much higher levels than in the untreated control, and the inducibility of tryptophan oxygenase gene expression by dexamethasone and glucagon was also preserved. Niacinamide tryptophan 2,3-dioxygenase Rattus norvegicus
2 In the nicotinamide-treated hepatocytes, albumin and tryptophan 2,3-dioxygenase mRNAs were present at much higher levels than in the untreated control, and the inducibility of tryptophan oxygenase gene expression by dexamethasone and glucagon was also preserved. Niacinamide tryptophan 2,3-dioxygenase Rattus norvegicus