Title : Expression and functional role of CD23 on T cells.

Pub. Date : 1989 Jan

PMID : 2522048






8 Functional Relationships(s)
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1 We have found that approximately 10%-15% of tonsil, but not peripheral blood, T cells express the CD23 antigen following activation with 12-O-tetradecanoylphorbol 13-acetate (TPA), phytohemagglutinin (PHA) or recombinant interleukin 4. Tetradecanoylphorbol Acetate Fc epsilon receptor II Homo sapiens
2 We have found that approximately 10%-15% of tonsil, but not peripheral blood, T cells express the CD23 antigen following activation with 12-O-tetradecanoylphorbol 13-acetate (TPA), phytohemagglutinin (PHA) or recombinant interleukin 4. Tetradecanoylphorbol Acetate Fc epsilon receptor II Homo sapiens
3 Similarly, SN from a CD23+ L cell transfectant augments the proliferative response of tonsil T cells to both TPA and PHA. Tetradecanoylphorbol Acetate Fc epsilon receptor II Homo sapiens
4 The CD23 molecule expressed by TPA-driven T cell blasts appears identical in size to the 45-kDa glycoprotein present on EBVLCL and activated B cells. Tetradecanoylphorbol Acetate Fc epsilon receptor II Homo sapiens
5 The results presented here demonstrate that CD23 is expressed on activated tonsil, but not peripheral blood T cells and plays a role, via the binding of CD23 mAb and CD23+ material, present in EBVLCL and CD23+ transfectant SN, in the regulation of T cell proliferation in response to mitogens such as PHA and TPA. Tetradecanoylphorbol Acetate Fc epsilon receptor II Homo sapiens
6 The results presented here demonstrate that CD23 is expressed on activated tonsil, but not peripheral blood T cells and plays a role, via the binding of CD23 mAb and CD23+ material, present in EBVLCL and CD23+ transfectant SN, in the regulation of T cell proliferation in response to mitogens such as PHA and TPA. Tetradecanoylphorbol Acetate Fc epsilon receptor II Homo sapiens
7 The results presented here demonstrate that CD23 is expressed on activated tonsil, but not peripheral blood T cells and plays a role, via the binding of CD23 mAb and CD23+ material, present in EBVLCL and CD23+ transfectant SN, in the regulation of T cell proliferation in response to mitogens such as PHA and TPA. Tetradecanoylphorbol Acetate Fc epsilon receptor II Homo sapiens
8 The results presented here demonstrate that CD23 is expressed on activated tonsil, but not peripheral blood T cells and plays a role, via the binding of CD23 mAb and CD23+ material, present in EBVLCL and CD23+ transfectant SN, in the regulation of T cell proliferation in response to mitogens such as PHA and TPA. Tetradecanoylphorbol Acetate Fc epsilon receptor II Homo sapiens