Pub. Date : 2013 Jul 15
PMID : 25206494
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Ethanol also increased p53 phosphorylation, followed by an increase in p21 tumor suppressor protein and a decrease in phospho-Rb (retinoblastoma) protein, leading to alterations in the expressions and activity of cyclin dependent protein kinases. | Ethanol | tumor protein p53 | Homo sapiens |
2 | Our results suggest that ethanol mediates apoptosis of SK-N-SH neuroblastoma cells by activating p53-related cell cycle arrest possibly through activation of the c-Jun N-terminal protein kinase-related cell death pathway. | Ethanol | tumor protein p53 | Homo sapiens |