Title : How does ethanol induce apoptotic cell death of SK-N-SH neuroblastoma cells.

Pub. Date : 2013 Jul 15

PMID : 25206494






2 Functional Relationships(s)
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1 Ethanol also increased p53 phosphorylation, followed by an increase in p21 tumor suppressor protein and a decrease in phospho-Rb (retinoblastoma) protein, leading to alterations in the expressions and activity of cyclin dependent protein kinases. Ethanol tumor protein p53 Homo sapiens
2 Our results suggest that ethanol mediates apoptosis of SK-N-SH neuroblastoma cells by activating p53-related cell cycle arrest possibly through activation of the c-Jun N-terminal protein kinase-related cell death pathway. Ethanol tumor protein p53 Homo sapiens