Title : Vitamin D attenuates cytokine-induced remodeling in human fetal airway smooth muscle cells.

Pub. Date : 2015 Jun

PMID : 25204635






2 Functional Relationships(s)
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1 Additionally, calcitriol attenuated TNFalpha and TGFbeta-induced collagen III expression and deposition, and separately, inhibited proliferation of fetal ASM cells induced by either inflammatory mediator. Calcitriol transforming growth factor beta 1 Homo sapiens
2 Overall, our data demonstrate that calcitriol can blunt multiple effects of TNFalpha and TGFbeta in developing airway, and point to a potentially novel approach to alleviating structural changes in inflammatory airway diseases of childhood. Calcitriol transforming growth factor beta 1 Homo sapiens