Title : Astrocyte elevated gene-1 (AEG-1) promotes osteosarcoma cell invasion through the JNK/c-Jun/MMP-2 pathway.

Pub. Date : 2014 Oct 3

PMID : 25204501






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 SP600125 (a JNK inhibitor) decreased phosphor-c-Jun and MMP-2 in U2OS-AEG-1, while PD98059 (a ERK1/2 inhibitor) had no influence on the levels of phosphor-c-Jun or MMP-2 in U2OS-AEG-1. pyrazolanthrone matrix metallopeptidase 2 Homo sapiens