Title : Omega-3 fatty acids inhibit the up-regulation of endothelial chemokines in maintenance hemodialysis patients.

Pub. Date : 2015 Feb

PMID : 25204316






3 Functional Relationships(s)
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1 Supplementation of omega-3 PUFAs effectively decreased the LPS-induced PBMC expression of RANTES (Regulated upon Activation, Normal T cell Expressed and Secreted) and MCP-1 (Monocyte Chemotactic Protein-1; unadjusted P = 0.04 and 0.06; adjusted for demographics P = 0.02 and 0.05, respectively). Fatty Acids, Omega-3 C-C motif chemokine ligand 2 Homo sapiens
2 Supplementation of omega-3 PUFAs effectively decreased the LPS-induced PBMC expression of RANTES (Regulated upon Activation, Normal T cell Expressed and Secreted) and MCP-1 (Monocyte Chemotactic Protein-1; unadjusted P = 0.04 and 0.06; adjusted for demographics P = 0.02 and 0.05, respectively). Fatty Acids, Omega-3 C-C motif chemokine ligand 2 Homo sapiens
3 CONCLUSIONS: The results of this pilot study suggest that supplementation of omega-3 PUFAs is beneficial in decreasing the levels of endothelial chemokines, RANTES and MCP-1. Fatty Acids, Omega-3 C-C motif chemokine ligand 2 Homo sapiens